The Center for Clinical Research was organized in January 2000 by Dr. Richard L. Rauck. We are a dedicated research facility for all phases of pharmaceutical clinical studies as well as device related studies. We take pride in conducting high-quality research as well as maintaining the well-being of our patients. The Center for Clinical Research partners with many private companies as well as the largest drug corporations to conduct groundbreaking research.

Our highly trained staff include a recruitment team, a regulatory team, and four study coordinators. The Center for Clinical Research is directed by Dr. Richard L. Rauck, and joined by attending physicians Dr. James North, Dr. Leo Kapural and Dr. Christopher Gilmore, and Dr. Kamal Ajam. These physicians also serve as principal investigators on all of our studies.

Research Studies

Amputee Pain

Is Residual/Phantom Limb Pain Holding You Back?

Volunteers with non-traumatic lower extremity amputations are needed for participation in a clinical research study.

Doctors and other medical professionals are currently exploring if small electrical pulses can reduce phantom limb and residual limb pain.  Electrical stimulation is small pulses of electricity that are sent to different parts of the body to improve function.  The electrical stimulation device being researched is an outpatient procedure, so you will be able to go home within that same day.

This study is being conducted to determine if high frequency stimulation can provide pain relief in people with non-traumatic post-amputation pain.  You may be eligible to participate in this study if:

  • You are 21 years of age or older/legally able to sign consent
  • Have had chronic post-amputation pain for at least 6 months that is resistant to pain medication
  • Drug therapy must be stable for at least 6 weeks prior to implant
  • Unilateral amputation lower extremity

There will be no additional costs to you for participating in this research study.  You will be compensated for your time.

To learn more, call 336-714-8388

Amputee

Are  you suffering from phantom limb or residual  limb pain >4 after a traumatic lower extremity amputation? The Center for Clinical Research has a clinical trial using a stimulator to test treatment for amputee pain! Study-related treatment is of no cost to you, and you could be compensated for your travel pertaining to the clinical trial.

To qualify you must:

  • Be 21 years or older
  • Have traumatic lower extremity amputation
  • Have phantom limb or residual limb pain of >4

If you are currently suffering from abdominal pain and would be interested in learning more about our research study please call 336-714-8388.

Chronic Low Back Pain

The Center for Clinical Research is currently enrolling patients with Chronic Low Back Pain to participate in one of several back pain studies conducted at their site.

Patients must have chronic low back pain with radiculopathy. These studies use an oral medication, injections, or a device to treat back pain.

Ages 18-70

Patients will be compensated for their participation within the study.

If interested and would like to learn more, call (336) 714-8388.

CRPS/RSD

As someone with Complex Regional Pain Syndrome (CRPS), also known as RSD, you know that there has been minimal treatment options for your condition. The Center for Clinical Research is conducting a research study using an oral medication to test a new treatment option for CRPS patients.

Our well-trained doctors are experts on CRPS and are the Principal Investigators over the study.

Participants must:

  • Be at least 18 years of age
  • Symptoms of CRPS of the upper or lower extremities within the last 2 years
  • Pain score of >4
  • Stable treatment /medication therapy for the last month with no intent to change
  • Regular dental exam within the last 6 months (will have to have)
  • Using two forms of contraception for women of child bearing potential at least one month prior to screening
  • Any other condition that could affect your ability to report your pain score
  • Able to speak English and understand how to use electronic diary

For more information, call (336)714-8388.

Diabetic Neuropathy

Have pain from Diabetic Peripheral Neuropathy(DPN)? Coming soon to the Center for Clinical Research is a study that aims to relieve that pain!

Participants must:

  • Be diagnosed with Type 1 or Type 2 Diabetes
  • Have pain that has lasted more than 5 months but no longer than 6 years
  • Be willing to come off pain medications specific to DPN

For more information, call (336) 714-8388.

Failed Back Surgical Syndrome

Still have low back pain after your back surgery? The Center for Clinical Research has a device-study that could help.

The clinical trial is using a spinal cord stimulator to test treatment for patients with failed back surgery.

You could qualify if:

  • You are 18 years or older
  • You have been diagnoised with Failed Back Surgical Syndrome (FBSS) for 12 months
  • You have no implanted devices
  • You have never had a spinal cord stimulator

For more information, call (336) 714-8388.

Osteoarthritis

Do you have osteoarthritis of the hip or knee?  We are seeking volunteers interested in participating in a clinical study on hip or knee pain due to osteoarthritis.

Our study uses an oral medication that aims to relieve the pain. You will be compensated for your time.

Patients must be:

  • 18 years of age or older
  • On a stable dose of naproxen, celebrex, or diclofenac
  • Willing to come off current pain medication in order to determine the effectiveness of the study drug

For more information about this study, please call 336-714-8388.

Low back pain

Do you have low back pain primarily in the L5 region?  We are seeking volunteers interested in participating in a clinical study of low back pain.

Our study uses cooled radio-frequency ablation that aims to relieve the pain. You will be compensated for your time.

Patients must be:

  • >21 years of age or older
  • BMI < 40
  • Low back pain primarily in the L5 region
  • On a stable dose of opioids for 2 months (equal to or > 60 mg/day MED)
  • Diagnosis of moderate to severe CLBP for 3 months
  • Willing to double barrier contraception
  • Previous SI joint injections >50% pain relief

For more information about this study, please call 336-714-8388.

Osteoarthritis of the knee

Do you have a diagnosis of osteoarthritis of the knee for > than 6 months?  We are seeking volunteers interested in participating in a clinical study of osteoarthritis of the knee.

Our study uses oral medication that aims to relieve the pain. You will be compensated for your time.

Patients must be:

  • 40-95 years of age or older
  • Have a diagnosis of OA of the knee for > 6 months
  • Failed treatment of Tramadol OR failed treatment/intolerance to opioids
  • Current opioids must be less than 15mg MED
  • Failed prior therapies; NSAIDS (specifically acetaminophen), opioids, duloxetine, IA corticosteroids, Physical therapy
  • Willing to stay on a stable dose of medication

For more information about this study, please call 336-714-8388.

Unilateral radicular leg pain

Do you have a diagnosis of unilateral radicular leg pain?  We are seeking volunteers interested in participating in a clinical study of radicular leg pain.

Our study uses epidural clonidine injection that aims to relieve the pain. You will be compensated for your time.

Patients must be:

  • Between the ages of 18-70 years old
  • Have a diagnosis of unilateral radicular leg pain; radiuclar leg pain is >6 and <9
  • Radiation into the leg
  • The leg pain must extend at least to the knee and be consistent with one of the dermatomal distributions noted
  • Radicular pain symptoms in the current episode must have been present for at last 8 weeks but no longer than 9 months at the time of screening
  • Eligible subjects must be able to distinguish and characterize the contribution of back and leg pain to their overall
  • Women of childbearing potential use acceptable birth control
  • Must be able to read, write, and understand English
  • Had an MRI or be willing to have one

For more information about this study, please call 336-714-8388.

Chronic primary axial back pain

Do you have a diagnosis of chronic, primary axial back pain?  We are seeking volunteers interested in participating in a clinical study of chronic primary axial back pain based on consultation with a spine surgeon or neurosurgeon.

Our study uses spinal cord simulation to relieve the pain. You will be compensated for your time.

Patients must be:

  • At least 18 years of age
  • Have a diagnosis of chronic, primary axial back pain based on consultation with a spine surgeon or neurosurgeon
  • Not candidates for or eligible for major lumbar spine surgery such as fusion, microdiscectomy, laminectomy, arthroplasty, etc; or present with spinal conditions for which surgery is typically indicated but must not be considered eligible for surgery due to lack of severity, lack of clearly identifiable structural cause, lack of desire to undergo major lumbar surgery or other factors
  • Pain score >5; should have a predominant neuropathic component
  • Have not had any surgery for back or leg pain or any surgery resulting in back or leg pain
  • Stable dose of pain medications for at least 28 days
  • Able to read and understand requirements
  • Able to use an electronic diary

For more information about this study, please call 336-714-8388.